Improved immune response of common carp (Cyprinus carpio) by administration of mahang sirap (Macaranga involucrate) Leaf Extract

Authors

  • Edi Ilimu Program Studi Pendidikan Kimia Universitas Sembilanbelas November Kolaka. Jl. Pemuda No. 339 Kabupaten Kolaka, Provinsi Sulawesi Tenggara, Indonesia
  • Saparuddin Saparuddin Program Studi Pendidikan Biologi Universitas Sembilanbelas November Kolaka. Jl. Pemuda No. 339 Kabupaten Kolaka. Provinsi Sulawesi Tenggara, Indonesia

DOI:

https://doi.org/10.51179/jipsbp.v5i1.1898

Keywords:

M. involucrata, Ikan_Mas, Respon_Imum, Jumlah_Leukosit, Fagositosis.

Abstract

This study aims to test the effectiveness of Macaranga involucrata leaf extract as an immune response in carp to increase the number of leukocytes and phagocytic activity. M. involucrata extract was injected intramuscularly into carp. The method used is Completely Randomized Design (CRD). This study was conducted with five treatments, each of which was repeated three times. The treatments were P1 = 1% (v/v), P2 = 4% (v/v), P3 = 8% (v/v), P4 = 12% (v/v) and P5 (negative control). The results showed that M. involucrata extract could respond to an increase in the number of leukocytes and an increase in phagocytic activity. Responses to an increase in the number of leukocytes (12.27 x 108 cells/mL) and phagocytic activity (45.41%) were found in P4 treatment. Based on this study it was concluded that M. involucrata extract showed an increase in the immune response of carp.

Downloads

Download data is not yet available.

References

Cui, L., Ma, Z., Wang, D., & Niu, Y. (2022). Ultrasound-assisted extraction, optimization, isolation, and antioxidant activity analysis of flavonoids from Astragalus membranaceus stems and leaves. Ultrasonics Sonochemistry, 90(October), 106190. doi: 10.1016/j.ultsonch.2022.106190

Effendi, N., & Widiastuti, H. (2014). Identifikasi aktivitas imunoglobulin M (Ig.M) ekstrak etanolik daun ceplukaN (Physalis Minima Linn.) pada mencit. Jurnal Kesehatan, 7(2), 353–360.

Ganda, A. N. F., Andoko, Setyarini, P. H., & Gapsari, F. (2018). The inhibitive effect of tannin in Psidium guajava leaves towards 304SS corrosion in concentrated HCl. Matec Web of Conferences, 204. doi: 10.1051/matecconf/201820405018

Handayani, N. (2018). Uji Aktivitas Fagositosis Makrofag Ekstrak Etanol Daun Suji (Dracaena angustifolia (Medik.)Roxb. ) Secara in vitro. Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ), 1(1), 26–32. doi: 10.35799/pmj.1.1.2018.19648

Ilimu, E., & Syah, Y. M. (2019). Turunan Senyawa Flavonoid dari Daun Macaranga involucrata (Roxb.) Baill dari Buton Tengah, Sulawesi Tenggara. In Jurnal Kimia Valensi (Vol. 5, Issue 1). doi: 10.15408/jkv.v5i1.7909

Kumazawa, S., Murase, M., Momose, N., & Fukumoto, S. (2014). Analysis of antioxidant prenylflavonoids in different parts of Macaranga tanarius, the plant origin of Okinawan propolis. Asian Pacific Journal of Tropical Medicine, 7(1), 16–20. doi: 10.1016/S1995-7645(13)60184-4

Lengka, K., Manoppo, H., & Kolopita, M. E. F. (2013). Peningkatan Respon Imun Non Spesik Ikan Mas (Cyprinus carpio L) Melalui Pemberian Bawang Putih (Allium Sativum). E-Journal Budidaya Perairan, 1(2), 21–28. doi: 10.35800/bdp.1.2.2013.1912

Lusiastuti, A. M., & Hardi, E. H. (2010). Gambaran darah sebagai indikator kesehatan pada ikan air tawar. Prosiding Seminar Nasional Ikan, 1, 65–69.

Manopo, H., & Magdalena E. P. Kolopita. (2016). Penggunaan ragi roti (. In Bududaya Perairan, 4(3): 37–47.

Manoppo, C. N. P. dan H. (2015). Peningkatan Respon Kebal Non-spesifik dan Pertumbuhan Ikan Nila. Jurnal Budidaya Perairan, 3(1), 11–18.

Octarina, Y., Prasetiyono, E., Febrianti, D., & Robin, R. (2018). Efektivitas ekstrak daun ciplukan (Physalis angulata L.) terhadap sistem kekebalan tubuh ikan nila (Oreochromis niloticus). Jurnal Riset Akuakultur, 13(3), 259. doi: 10.15578/jra.13.3.2018.259-265

Pasaribu, W., & Longdong, S. N. . (2019). Efektivitas Ekstrak Daun Pacar Air (Impatiens balsamina L.) Untuk Meningkatkan Respon Imun Non Spesifik Ikan Nila (Oreochromis niloticus). E-Journal Budidaya Perairan, 3(1), 83–92. doi: 10.35800/bdp.3.1.2015.6939

Ramadhan, R., & Sari, L. A. (2018). Teknik pembenihan ikan mas (Cyprinus carpio) secara alami di unit pelaksana teknis pengembangan budidaya air. Journal of Aquaculture and Fish Health, 7(3), 124–132. doi: 10.20473/jafh.v7i3.11261

Raman, R. P. (2017). Applicability, Feasibility and Efficacy of Phytotherapy in Aquatic Animal Health Management. American Journal of Plant Sciences, 08(02), 257–287. doi: 10.4236/ajps.2017.82019

Rawung, M. E., & Manoppo, H. (2014). Penggunaan ragi roti (Saccharomyces cereviciae) secara in situ untuk meningkatkan respon kebal non-spesifik ikan nila (Oreochromis niloticus). E-Journal Budidaya Perairan, 2(2). doi: 10.35800/bdp.2.2.2014.4901

Rejeki, M. S., Sasanti, A. D., & Taqwa, F. H. (2018). Pemanfaatan tepung paci-paci (Leucas lavandulaefolia) untuk mengobati infeksi Aeromonas hydrophila pada ikan patin (Pangasius sp.). Jurnal Akuakultur Rawa Indonesia, 6(2), 165–176. doi: 10.36706/jari.v6i2.7160

Saparuddin, S., Yanti, Y., Salim, S., & Muhammad, H. (2020). Hematological response of Tilapia (Oreochromis niloticus) in Laundry wastewater. Biogenesis: Jurnal Ilmiah Biologi, 8(1), 69–78. doi: 10.24252/bio.v8i1.13137

Sarjito, Prayitno, S. B., & Haditomo, A. H. C. (2013). Buku Pengantar Parasit dan Penyakit Ikan. Buku Pengantar Parasit Dan Penyakit Ikan, 1–92.

Satyantini, W., Agustono, A., Arimbi, A., Sabdoningrum, E., Budi, M., & Asmi, L. (2016). Peningkatan Respons Imun Non Spesifik Ikan Gurame Pascapemberian Ekstrak Air Panas Mikroalga Spirulina platensis (enhancement of non-specific immune response of osphronemus gouramy after giving of hot water extract spirulina platensis). In Jurnal Veteriner, 17(I3): 347–354).

doi: 10.19087/jveteriner.2016.17.3.347

Susanti, R., & Yuniastuti, A. (2012). Aktivitas Reactive Oxygen Species Makrofag Akibat Stimulasi Gel Lidah Buaya Pada Infeksi Salmonella Typhimurium. 35(1).

Published

2023-05-02

How to Cite

Ilimu, E., & Saparuddin, S. (2023). Improved immune response of common carp (Cyprinus carpio) by administration of mahang sirap (Macaranga involucrate) Leaf Extract. Arwana: Jurnal Ilmiah Program Studi Perairan, 5(1), 51–56. https://doi.org/10.51179/jipsbp.v5i1.1898

Issue

Section

Articles